In continuation of the established series of successful ISREC Symposia on various aspects of cancer, we will have a
more focused conference in 2014 on metastasis. While the lethal impact of acquiring this hallmark capability during tumor
progression has long been recognized, only in recent years have we begun to learn about the specific determinants that govern
the process of tumor growth at secondary sites. Thus, the focus of this conference will be on determinants enabling the initial
outgrowth of tumor cells in a novel site, the heterotypic tumor micro-environment of metastatic lesions, as well as the
prospect for and progress toward therapeutic targeting of metastatic lesions.